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ANTIBODY, D2E7
Descriptors Found:
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DeCS
Descriptor
English
:
Adalimumab
Descriptor
Spanish
:
Adalimumab
Descriptor
Portuguese
:
Adalimumab
Synonyms
English
:
D2E7 Antibody
Humira
Antibody, D2E7
Tree Number:
D12.776.124.486.485.114.224.060.250
D12.776.124.790.651.114.224.060.250
D12.776.377.715.548.114.224.200.250
Definition
English
:
A humanized monoclonal antibody that binds specifically to TNF-ALPHA and blocks its interaction with endogenous TNF RECEPTORS to modulate
INFLAMMATION
. It is used in the treatment of
RHEUMATOID ARTHRITIS
; PSORIATIC
ARTHRITIS
; CROHN'S
DISEASE
and ULCERATIVE
COLITIS.
See Related
English
:
Tumor Necrosis Factor-alpha
History Note
English
:
2016 (2002)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55973
Unique Identifier:
D000068879
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS